Motif ID: MEF2{A,B,C,D}.p2

Z-value: 1.321


Transcription factors associated with MEF2{A,B,C,D}.p2:

Gene SymbolEntrez IDGene Name
MEF2A 4205 myocyte enhancer factor 2A
MEF2B 100271849 myocyte enhancer factor 2B
MEF2BNB-MEF2B 4207 MEF2BNB-MEF2B readthrough
MEF2C 4208 myocyte enhancer factor 2C
MEF2D 4209 myocyte enhancer factor 2D

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MEF2Dchr1_-_1564705060.883.5e-03Click!
MEF2Achr15_+_100106132-0.801.8e-02Click!
MEF2Bchr19_-_19281090,
chr19_-_19281062		0.782.2e-02Click!
MEF2Cchr5_-_88119604-0.658.3e-02Click!
MEF2BNB-MEF2Bchr19_-_19303222-0.581.3e-01Click!


Activity profile for motif MEF2{A,B,C,D}.p2.

activity profile for motif MEF2{A,B,C,D}.p2


Sorted Z-values histogram for motif MEF2{A,B,C,D}.p2

Sorted Z-values for motif MEF2{A,B,C,D}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MEF2{A,B,C,D}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_41742666 3.576 NM_002192
 INHBA
inhibin, beta A
chr18_+_29027731 3.287 NM_001944
 DSG3
desmoglein 3
chr20_+_58251715 2.982 NM_001199506
 PHACTR3
phosphatase and actin regulator 3
chr10_+_118187381 2.377 NM_001011709
 PNLIPRP3
pancreatic lipase-related protein 3
chrX_-_117107700 1.831 NM_033495
NM_001168300
 KLHL13

kelch-like 13 (Drosophila)

chr14_-_105634708 1.725 JAG2
jagged 2
chr14_+_39735871 1.657 CTAGE5
CTAGE family, member 5
chr14_-_61748510 1.527 NM_001017970
 TMEM30B
transmembrane protein 30B
chr12_-_28124915 1.452 NM_002820
NM_198965
 PTHLH

parathyroid hormone-like hormone

chr15_+_40531236 1.423 PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr6_-_136847609 1.370 MAP7
microtubule-associated protein 7
chr15_+_40509628 1.331 NM_001128628
NM_001128629
 PAK6

p21 protein (Cdc42/Rac)-activated kinase 6

chr5_-_16509106 1.290 NM_019000
 FAM134B
family with sequence similarity 134, member B
chr7_+_18126543 1.271 NM_001204144
 HDAC9
histone deacetylase 9
chr1_+_13911966 1.238 NM_001006624
NM_001006625
 PDPN

podoplanin

chr17_-_56492938 1.187 RNF43
ring finger protein 43
chr17_-_74483806 1.182 NM_001005498
 RHBDF2
rhomboid 5 homolog 2 (Drosophila)
chr6_-_136847078 1.152 NM_001198608
NM_001198609
NM_001198611
 MAP7


microtubule-associated protein 7


chr11_+_1860718 1.142 NM_001145829
 TNNI2
troponin I type 2 (skeletal, fast)
chr19_+_45281125 1.140 NM_001130852
NM_012116
 CBLC

Cas-Br-M (murine) ecotropic retroviral transforming sequence c


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
1.53 5.83e-03 GO:0002376 immune system process

Gene overrepresentation in compartment category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
5.80 3.34e-02 GO:0032982 myosin filament
2.83 2.55e-03 GO:0030016 myofibril
2.74 2.62e-02 GO:0030017 sarcomere
2.67 6.74e-03 GO:0043292 contractile fiber
2.64 1.85e-02 GO:0044449 contractile fiber part

Nothing significant found in function category.